Sir Ganga Ram Hospital deciphers Blood Barriers for COVID Infection

In a breakthrough study, the hospital finds blood A, B &Rh+ @ high risk

New Delhi: An original research article (attached), conducted by Department of Research and Department of Blood Transfusion Medicine at Sir Ganga Ram Hospital has found that blood groups A, B and Rh+ are more susceptible to COVID-19 infection whereas O, AB and Rh- are at lower risk of Covid-19 infection. It also found that there is no association between blood groups and susceptibility to severity of disease as well as mortality.

This research has been published in November 21 edition of “Frontiers in Cellular and Infection Microbiology”.

According to Dr. Rashmi Rana, Consultant, Department of Research, Sir Ganga Ram Hospital, New Delhi, “severe acute respiratory syndrome coronavirus 2 is a new virus, and it is unclear whether blood groups have any impact on Covid-19 risk or progression. Therefore, we investigated the association of ABO and Rh blood group with Covid-19 susceptibility, prognosis, recovery time, and mortality in this study.”

The study was conducted on total of 2,586 Covid-19 positive patients tested through real-time PCR who were admitted at SGRH from April 8, 2020 to October 4, 2020.

According to Dr. Vivek Ranjan, Co-author and Chairperson, Department of Blood Transfusion, Sir Ganga Ram Hospital, New Delhi, “We also found that male patients of blood group B are more prone to Covid-19 than the female patients with blood group B and Blood Group AB was observed to be more susceptible to infection in patients with age group ≤ 60 years.”

Our study also found that Blood Group A and Rh + types are associated with a decrease in recovery period, whereas Blood Group O & Rh- are associated with increase in recovery period. However, the ABO and/or Rh blood groups may not be responsible for this association, as these may indicate an unexplored underlying factor like co-morbidity. Therefore, larger, multicenter, and prospective studies are needed to ascertain the relationship of between blood groups and SARS-CoV-2.

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