Govt Job in Science & Technology at Central Drug Research Institute

CSIR-Central Drug Research Institute, Lucknow, a premier Institute under Council of Scientific and Industrial Research CSIR is involved in multidisciplinary R&D programs of both basic and applied nature. CSIR-CDRI is a pioneer biomedical research organization in India and has the infrastructure and expertise to develop a drug from concept to commercialization.

Senior Scientist
Area : Medicinal and Process Chemistry
Post Code : 001
No of Posts & Reservation : 1 UR
Age Limit & Emoluments : Age limit : 37 Pay Matrix Level-12
Essential Educational Qualifications & Experience : PhD in the area of Chemistry / Chemical Sciences with 2 years’ experience in the area of Medicinal Chemistry

Desirable Experience : State of the art knowledge in modern synthetic Medicinal chemistry. Experience in designing chemical compounds for biologically activity and data analysis. Synthetic biology in the context of drug designing and drug discovery. A record of publications and/or patents demonstrating proficiency in synthetic chemistry and drug discovery.
Job Specification# : Design and synthesis of novel chemical compounds for target based drug discovery.

Senior Scientist
Area : Natural Product Chemistry
Post Code : 002
No of Posts & Reservation : 1 UR
Age Limit & Emoluments : Age limit : 37 Pay Matrix Level-12
Essential Educational Qualifications & Experience : PhD in the area of natural sciences with two years research experience in the area of Natural Products Chemistry

Desirable Experience : Doctoral work in the area of natural products chemistry / phytochemistry / marine chemistry / microbial chemistry or pharmacognosy with proven competence and experience in screening, extraction, isolation and characterization of natural products; use of modern analytical and spectroscopic techniques
Job Specification# : To conduct R&D in medicinal Chemistry / natural product chemistry aimed towards new drug discovery and development from natural resources for life style Diseases / infectious Diseases / Reproductive Health. Appointees are expected to take up consultancy and industry sponsored R&D project activities.

Scientist
Area : Neuroscience
Post Code : 003
No of Posts & Reservation : 1 UR
Age Limit & Emoluments : Age limit : 37 Pay Matrix Level-12
Essential Educational Qualifications & Experience : MD/MVet Pharmacology / Neuropharmacology. OR PhD(submitted) in any area of Neurosciences
Desirable Experience : First hand working experience in human IPSs and human NSC, Rodent NSCs, Brain organoids, Brain on chip. Brain Ca++ imaging in live animals and ontogenetic stimulation and recording of neurobehaviors.
Job Specification# : Conduct fundamental neurobiology experiments to discover druggable target and pathways. Development of new assay system to screen NCEs for drug discovery for CNS diseases

Scientist
Area : Endocrinology and Metabolic Diseases
Post Code : 004
No of Posts & Reservation : 1 UR
Age Limit & Emoluments : Age limit : 37 Pay Matrix Level-13
Essential Educational Qualifications & Experience : MD/MVet Pharmacology / Neuropharmacology. OR PhD(submitted) in any area of Neurosciences
Desirable Experience : Experience in diabetic vascular complications with epigenetic contributions
Job Specification# : Research in the area of fundamental basis of metabolic disorder using cellular, model systems and patient samples.

Principal Scientist
Area : Cancer
Post Code : 005
No of Posts & Reservation : 1
Age Limit & Emoluments : Age limit: 45 Pay Matrix Level-13
Essential Educational Qualifications & Experience : PhD in any area of life sciences with minimum 3 yrs research experience in Cancer Biology
Desirable Experience : Experience in tumor animal models, Patient derived xenografts. Proven track record / success in independent grant applications in the area of Cancer Biology
Job Specification# : Cancer Biology, Patient derived mouse model, Drug Discovery.

Senior Scientist
Area : Cancer
Post Code : 006
No of Posts & Reservation : 1
Age Limit & Emoluments : Age limit: 37 Pay Matrix Level-12
Essential Educational Qualifications & Experience : PhD in any area of life sciences with minimum 2 yrs research experience in Cancer Biology
Desirable Experience : Cancer genomics, RNA seq, ChIP seq analyses, molecular modeling, target based drug discovery.
Job Specification# : Cancer Genomics / Ageing & Cancer

Senior Scientist
Area : Clinical Pharmacology
Post Code : 007
No of Posts & Reservation : 1
Age Limit & Emoluments : Age limit: 37 Pay Matrix Level-12
Essential Educational Qualifications & Experience : MD with 3 years’ experience pharmacology / medicine. OR MBBS +PhD in any area of life sciences
Desirable Experience : MD in Pharmacology / Medicine with clinical research experience in lifestyle disorders (of CVS-CNS & the metabolic axis) and experience in IND documentation and clinical trial design
Job Specification# : Complement pre-clinical research to validate novel drug targets for lifestyle disorders; Preparation of IND documents for submission to regulatory agencies, design of clinical trials for molecules under development.

Scientist
Area : Clinical Pharmacology
Post Code : 008
No of Posts & Reservation : 1 ST (Backlog)
Age Limit & Emoluments : Age limit: 32 Pay Matrix Level-11
Essential Educational Qualifications & Experience : MD in Pharmacology, experience in IND documentation and clinical trial design
Desirable Experience : MD in Pharmacology / Medicine with clinical research experience in lifestyle disorders (of CVS-CNS & the metabolic axis) and experience in IND documentation and clinical trial design
Job Specification# : Preparation of IND documents for submission to regulatory agencies, design of clinical trials for molecules under development, perform clinical research for value addition to CDRI drugs.

Senior Scientist
Area : Toxicology & Experimental Medicine
Post Code : 009
No of Posts & Reservation : 1 UR
Age Limit & Emoluments : Age limit: 37 Pay Matrix Level-12
Essential Educational Qualifications & Experience : PhD in the area of Pharmaceutical Sciences/ Life Sciences with two years research experience in the area of drug delivery and /or quality control

Desirable Experience : PhD thesis incorporating development of drug delivery systems and validation of bio-analysis by HPLC or LC-MS or LC-MS/MS; experience in the pharmaceutical industry in the area of delivery systems and bio-analytical methods for pharmacokinetic metabolite identification OR post-doctoral research experience, published work of high quality in respect of novel strategies of formulation development and drug delivery systems and biomedical analysis; experience in animal handling OR approved chemist (by state Licensing Authority/CDSCO

Job Specification# : Development of formulations and delivery systems in line with CDRI mandate and to develop and validate analytical methods for API, formulations, blood, plasma/serum and tissue samples as per regulatory requirements, design and conduct of clinical and pre-clinical studies on pharmacokinetics in rodents and non-human primates, pharmacokinetic modeling, metabolite identification.

Senior Scientist
Area : Pharmaceutics and Pharmaco kinetics
Post Code : 010
No of Posts & Reservation : 1 UR
Age Limit & Emoluments : Age limit: 37 Pay Matrix Level-12
Essential Educational Qualifications & Experience : PhD in the area of Pharmaceutical Sciences/ Life Sciences with two years research experience in the area of drug delivery and /or quality control

Desirable Experience : PhD thesis incorporating development of drug delivery systems and validation of bio-analysis by HPLC or LC-MS or LC-MS/MS; experience in the pharmaceutical industry in the area of delivery systems and bio-analytical methods for pharmacokinetic metabolite identification OR post-doctoral research experience, published work of high quality in respect of novel strategies of formulation development and drug delivery systems and biomedical analysis; experience in animal handling OR approved chemist (by state Licensing Authority/CDSCO

Job Specification# : Development of formulations and delivery systems in line with CDRI mandate and to develop and validate analytical methods for API, formulations, blood, plasma/serum and tissue samples as per regulatory requirements, design and conduct of clinical and pre-clinical studies on pharmacokinetics in rodents and non-human primates, pharmacokinetic modeling, metabolite identification.

Senior Scientist
Area : Pharmaceutics and Pharmaco kinetics
Post Code : 011
No of Posts & Reservation : 1 UR
Age Limit & Emoluments : Age limit: 37 Pay Matrix Level-12
Essential Educational Qualifications & Experience : PhD in the area of Structural Biology/ Biophysics/ Biochemistry, or related discipline with minimum 2 years’ experience in the area of high resolution structure determination of biological macromolecules using Cryo-EM techniques and expertise in Generation, optimisation and analysis of negative stain and cryo-EM grids, Processing of single particle cryo-EM data and familiarity with cryo-EM software packages, performing single particle cryo-EM on a range of targets, Expression, purification and characterisation of proteins and/or protein complexes, for carrying out fundamental drug discovery and research including Fragment-based and Structure-based drug-discovery.

Desirable Experience : Outstanding experience in all aspects of cryoEM and single particle analysis, from construct design through structure refinement, to pursue a number of potential drug targets. Experience in macromolecular X-ray crystallography/ Small-Angle-Xray Scattering is desirable.

Job Specification# : Pursue independent research projects focused on exploring the structure and molecular mechanism of proteins of therapeutic interest to the Institute, primarily using high resolution Cryo-EM methods. Develop strong multi-disciplinary collaborations for research and translation in Drug discovery and therapeutic targets characterization

c. Scientists may also be permitted to undertake consultancy and sponsored R&D project activity as per CSIR rules. These activities give them scope to earn consultancy fee and honorarium as per CSIR guidelines governing these activities. Opportunities also exists for foreign deputations for training/presentation of papers/specific assignments etc.
d. CSIR provides excellent opportunities to deserving candidates for career advancement under Assessment Promotion scheme for Scientists. e. Deserving candidates may be considered for advance increment as per CSIR Rules.

How to apply
a. Eligible candidates are required to fill the application form ONLINE by accessing the link ‘SCIENTIST RECRUITMENT-07/2021’ available on CDRI website cdri.res.in The printout of the application, generated after Online submission is to be sent to CDRI with all the relevant enclosures before 20, Sept., 2021, 17:30 Hrs. IST.
b. For online application process please refer ‘How-to-apply Online’ instructions, ‘Fee Payment Procedure’ and ‘Application Replica’ available on the above-mentioned website.
c. The application is to be submitted in four distinct steps, as below:

1. Registration (online)
2. Fee Submission (online)
3. Application Submission (online) 4. Dispatch of physical copy of online application with original signature (manual)
d. The datelines for the above-mentioned stages of application is as follows:
Start Date for Registration for Online Application : Monday, 19 July 2021; 13:00 Hrs IST
Last Date for Registration, Fee Submission and Online Application : Friday, 27 August 2021; 17:30 Hrs IST
Last date of Receipt of physical copy of application at CDRI : Monday, 20 September 2021; 17:30 Hrs IST

e. Candidates are required to pay application fee of Rs. 100/- as per ‘Fee payment procedure’ available on the website. The candidates belonging to SC/ST/PWD/Women/Other Gender/CSIR Employees are exempted from submission of application fee.

f. In case of universities/institute awarding CGPA/SGPA/OGPA grades etc., candidates are requested to convert the same into percentage based on the formula as per their university/institute guidelines.

g. The print-out of the application, generated after online submission, duly accompanied by self-attested copies of the requisite certificates, mark sheets, age proof, education qualifications, experience, re-prints of 1st page of publications and caste certificate, if applicable, along with one recent colored passport size self-signed photograph affixed should be sent in an envelope super-scribed “APPLICATION FOR THE POST OF ____________ (Post Code ________)” by post to “ The Director, CSIR-Central Drug Research Institute, Sector 10, Jankipuram Extension, Sitapur Road, Lucknow – 226031, Uttar Pradesh, India”. Candidates applying for more than one post must submit each application in separate envelope for each post indicating the Code No. of the post.

h. Application once made will not be allowed to be withdrawn and fees once paid will not be refunded on any count nor can it be held in reserve for any other recruitment or selection process.

i. Applications from employees of Government Departments will be considered only if forwarded through proper channel, certified by the employer that the applicant, if selected will be relieved within one month of the receipt of the appointment orders. Also, vigilance clearance should also be submitted. However, advance copy of the application may be submitted before 20 Sept., 2021, 17:30 Hrs IST :30 Hrs IST :30 Hrs IST. Applications routed through proper channel should reach CSIR-CDRI before date of outcome.

j. Candidates should specifically note that the applications received after the closing date for any reason whatsoever (such as envelopes wrongly addressed, delivered elsewhere, postal delay etc.) will not be entertained by CSIR-CDRI.

k. Incomplete applications (i.e. without photograph, unsigned and applicable testimonials etc.) will not be entertained and will be summarily rejected.

Following documents must be attached along with the physical/hard copy(print-out) of online application form sent by post:
A. Coloured photograph pasted on the form and signed across in full.
B. Self-Attested photocopy of 10th / 12th class certificate indicating Date of Birth.
C. Self-Attested photocopies of all education qualifications certificates as well as mark sheets.
D. Self-Attested photocopy of Caste, EWS& PwD certificate, if applicable.
E. Self-Attested photocopies of experience certificates, if any.
F. Recommendations of the referees, if any
G. All other supportive documents in support of the application

Start Date for Registration for Online Application : Monday, 19 July 2021; 13:00 Hrs IST
Last Date for Registration, Fee Submission and Online Application : Friday, 27 August 2021; 17:30 Hrs IST
Last date of Receipt of physical copy of application at CDRI : Monday, 20 September 2021; 17:30 Hrs IST

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